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Data File: LAUPUA01

Data Files (1):

LAUPUA01_d1 - 26 Plutonium Exposed LANL Workers 42 yr

Study Name: Follow-Up Study for the Manhattan Project Plutonium Workers

Cohort Size: 26

Races: White

Sexes: Male

Diseases: Cancer and Non-Cancer Mortality

Earliest Exposure: 01/01/1944

Latest Exposure: 12/31/1945

Follow-Up: 12/31/1987

Exposure Type: Aerosol

Exposure Agent: Plutonium-239

Covariate: No data available.

Sites: Los Alamos National Laboratory

Description:
The purpose of this study was to maintain long-term surveillance of a group of workers exposed to plutonium-239, in order to estimate the plutonium deposition throughout their lifetime and to maintain detailed medical records. The information can then be compared with existing plutonium dosimetry models, radiobiological information, and human epidemiologic studies of plutonium workers. This data file set, prepared for studies by George Voelz, et al., consists of a single analytic file containing data taken from personnel records of 26 white males who were employed by the Manhattan Project (Los Alamos, New Mexico, now Los Alamos National Laboratory) during World War II. These data were used in this surveillance study of plutonium workers. These subjects were exposed to plutonium-239 from 1944 through 1945 during chemical and metallurgical research dealing with plutonium, as well as the fabrication of plutonium parts.
The plutonium work in 1944 to 1945 was partly done in chemical fume hoods, but some operations were performed in open rooms. Contamination of the work rooms with plutonium resulted from these operations. Inhalation of plutonium particles was the principal mode of exposure for this group of workers. These plutonium-exposed workers have had medical examinations approximately every 5 years since 1952. This data file was developed for the 1986 to 1987 examination records, at which time four of the subjects had died. There were three additional deaths before the data were submitted to CEDR. The information was obtained from personnel records and from continued personal contact with each of the 26 study subjects.
This file, LAUPUA01_d1, was developed for the fourth study in a series of studies documenting the health experience and possible effects of exposure for the 26 subjects. The selection of the 26 subjects was based on the history of individual job assignments, work conditions, and the results of plutonium measurements in urine samples taken during that period. The variables available include date of birth, date of death, cause of death (ICDA8), and hire and term dates.

Citations Associated:
Hempelmann, L. H., Langham, W. H., Richmond, C. R., & Voelz, G. L. (1973). Manhattan project plutonium workers: A twenty-seven year follow-up study of selected cases. Health Physics. https://doi.org/10.1097/00004032-197311000-00001
Hempelmann, L.H., Langham, W.H., Voelz, G.L., Richmond, C.R. (1973). Metabolism of uranium and transuranium elements: biomedical follow-up of the Manhattan Project plutonium workers. U.S. Atomic Energy Commission (AEC).
Voelz, G. L., Stevenson, A. P., & Stewart, C. C. (1989). Does plutonium intake in workers affect lymphocyte function? Radiation Protection Dosimetry. https://doi.org/10.1093/oxfordjournals.rpd.a080408
Voelz, G. L., Wilkinson, G. S., Acquavella, J. F., Tietjen, G. L., Brackbill, R. N., Reyes, M., & Wiggs, L. D. (1983). An update of epidemiologic studies of plutonium workers. Health Physics. https://doi.org/10.1097/00004032-198306001-00048
Voelz, G.L., Wilkinson, G.W., Healy, J.W., McInroy, J.F., Tietjen, G.L. (1983). Mortality study of Los Alamos workers with higher exposures to plutonium. Los Alamos National Laboratory, Health Physics Society 16th Midyear Topical Meeting.
Voelz, George L., & Lawrence, J. N. P. (1991). A 42-y medical follow-up of manhattan project plutonium workers. Health Physics. https://doi.org/10.1097/00004032-199108000-00001
Voelz, George L., Grier, R. S., & Hempelmann, L. H. (1985). A 37-year medical follow-up of manhattan project pu workers. Health Physics. https://doi.org/10.1097/00004032-198503000-00001
Voelz, George L., Hempelmann, L. H., Lawrence, J. N., & Moss, W. D. (1979). A 32-year medical follow-up of manhattan project plutonium workers. Health Physics. https://doi.org/10.1097/00004032-197910000-00001
Voelz, George L., Lawrence, J. N. P., & Johnson, E. R. (1997). Fifty years of plutonium exposure to the Manhattan project plutonium workers: An update. Health Physics. https://doi.org/10.1097/00004032-199710000-00004

Citations Associated:

Hempelmann, L. H., Langham, W. H., Richmond, C. R., & Voelz, G. L. (1973). Manhattan project plutonium workers: A twenty-seven year follow-up study of selected cases. Health Physics. https://doi.org/10.1097/00004032-197311000-00001

Hempelmann, L.H., Langham, W.H., Voelz, G.L., Richmond, C.R. (1973). Metabolism of uranium and transuranium elements: biomedical follow-up of the Manhattan Project plutonium workers. U.S. Atomic Energy Commission (AEC).

Voelz, G. L., Stevenson, A. P., & Stewart, C. C. (1989). Does plutonium intake in workers affect lymphocyte function? Radiation Protection Dosimetry. https://doi.org/10.1093/oxfordjournals.rpd.a080408

Voelz, G. L., Wilkinson, G. S., Acquavella, J. F., Tietjen, G. L., Brackbill, R. N., Reyes, M., & Wiggs, L. D. (1983). An update of epidemiologic studies of plutonium workers. Health Physics. https://doi.org/10.1097/00004032-198306001-00048

Voelz, G.L., Wilkinson, G.W., Healy, J.W., McInroy, J.F., Tietjen, G.L. (1983). Mortality study of Los Alamos workers with higher exposures to plutonium. Los Alamos National Laboratory, Health Physics Society 16th Midyear Topical Meeting.

Voelz, George L., & Lawrence, J. N. P. (1991). A 42-y medical follow-up of manhattan project plutonium workers. Health Physics. https://doi.org/10.1097/00004032-199108000-00001

Voelz, George L., Grier, R. S., & Hempelmann, L. H. (1985). A 37-year medical follow-up of manhattan project pu workers. Health Physics. https://doi.org/10.1097/00004032-198503000-00001

Voelz, George L., Hempelmann, L. H., Lawrence, J. N., & Moss, W. D. (1979). A 32-year medical follow-up of manhattan project plutonium workers. Health Physics. https://doi.org/10.1097/00004032-197910000-00001

Voelz, George L., Lawrence, J. N. P., & Johnson, E. R. (1997). Fifty years of plutonium exposure to the Manhattan project plutonium workers: An update. Health Physics. https://doi.org/10.1097/00004032-199710000-00004

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